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FIGLU – kwas bynajmniej niefiglarny

Niedobór witaminy B2, folianów i FIGLU #NietylkoMTHFR #witaminaB2 #FIGLU Chyba każdy z nas słyszał, jak ważny jest kwas foliowy. Na pewno wiedzą o tym kobiety, zwłaszcza te, które planują ciążę. Jest to jedna z pierwszych rzeczy, jakie mówi im ginekolog: „Musi Pani przyjmować kwas foliowy, bo to niezbędne, by mózg dziecka rozwijał się prawidłowo”. Niestety, nie wszyscy jesteśmy tacy sami. Mamy różne geny. Nawet ci z nas, którzy nie mają choroby genetycznej mogą być nosicielami pewnych nieprawidłowości – nazywają się one polimorfizmami. Nazwa polimorfizm (z angielskiego – SNP, czyli single nucleotide polimorfism) oznacza, że jest pewna „uroda genetyczna”, która dotyczy dużej części populacji. W ostatnich latach naukowcy odkryli, iż jednym z takich często spotykanych polimorfizmów jest wariant genu MTHFR (czyli […]

Autoimmunologia a bakterie jelitowe

Odnotowujemy ostatnio duży wzrost chorób autoimmunologicznych. Winni poszukiwani! Naukowcy ostatnio podkreślają rolę bakterii Enterococcus gallinarum, która migruje z jelita poprzez węzły chłonne i wątrobę do narządów, powodując reakcje organizmu przeciwko własnym tkankom. Dla mnie to jeszcze jeden z wielu winnych – znamy przecież reakcje autoimmunologiczne na swojską pałeczkę yersinii, która bytuje w przewodzie pokarmowym świń i łatwo rozmnaża się w mięsie. Powoduje niecharakterystyczną biegunkę, która mija sama – jednak bakteria ta potrafi przetrwać w nabłonku jelita, w węzłach chłonnych, ba! nawet w komórkach układu odpornościowego, które po pożarciu tego sprytnego mikroba same cierpią na “niestrawność” – bo bakteria żyje w ich wnętrzu. Co gorsza – gruz z pozostałości strawionych komórek yersinii, tzw LPSy bakteryjne, odkładają się w tkankach powodując atak układu odpornościowego. […]

Serotonin and autism

Serotonin is a link between a sick intestine and the brain in autism, scientists suggest. The neurotransmitter serotonin, also called “the happiness hormone,” is often present in excessive amounts in autistic patients. Unfortunately, it does not make them happier… Serotonin syndrome is well-known in medicine. It is a state when there is too much of the neurotransmitter in the brain. It most commonly occurs in patients with an overdose of antidepressants, or in people taking 5-HTP (5- Hydroxytryptophan). It can be lethally dangerous. Scientists researching the matter of autism agree on one thing: the serotonin levels are elevated in all autistic patients. This can be detected by blood serum test, content of serotonin in blood platelets, as well as urine […]

Urine testing for calcium oxalates

Calcium oxalates are organic substances, present in many plants and other commonly eaten products. They are present in dock, asparagus, rhubarb, beets, dark beer, cocoa, coffee, tea, and others. The third of calcium oxalates found in urine comes from the digestive system, and the remaining two thirds from metabolic processes in the liver. This makes the presence of oxalates in a morning urine sample all but useless for diagnostic purposes. In order to estimate if the oxalate content in urine calls for treatment, the test must be conducted on an all-day urine sample, because only it can be compared to laboratory norms. At the IIM Arcana, such a test can be performed. It is useful only if, in a few […]

Alcohol and the brain

Some food for thought for the weekend: what alcohol does to our brain. An adult, healthy body is able to metabolize only (or perhaps: as many as) one drink per hour. If the amount of alcohol in the body is higher than the current detoxification capability of the liver, then acetaldehyde is produced by alcohol dehydrogenase enzymes. Acetaldehyde is more toxic than ethanol and acetic acid, and it is the main reason for alcohol overdose symptoms—more commonly known as a hangover. What is interesting is that the presence of alcohol/acetaldehyde changes the function of GABA-dependent neurons in a way similar to autism. Also, in the CSA stool analysis we often see elevated levels of acetic acid. Similar intermediate parameters of […]

What is an autistic regress?

What is an autistic regress? Losing once-gained skills, understanding, speech… What is its background? We know that the inventor of the term “autism,” Kanner, blamed the parents. Even today in some circles just mentioning the search of roots of autistic regress is enough to risk ridicule and criticism. However, is there anything strange about posing a question, which medicine has been asking for ages? More and more scientists and doctors see the need for finding the reasons of regress, looking for factors in toxicity, immunology, contagions, or malnutrition—all of which also contribute to central nervous system disorders. Also epilepsy attacks may impair the functioning of autistic children.

Vitamin B12 levels

I often see patients who tried to inject vitamin B12 by themselves, and it turns out their blood serum levels for B12 are exceeded. They believe, that such a high level means they ingested too much of it with food. Of course, they believe that their bodies are perfectly saturated with B12 and that these stockpiles may last for long. Is it true? Let us take a look at some facts. What are the best tests used to check for B12 deficiency? Sadly, checking the blood serum levels will not yield the expected answer. Even worse, it may mislead the patient. An elevated level of B12 in blood serum, or hypercobalaminemia, is a common occurrence, and it usually accompanies tissue […]

New Service on Offer

More and more laboratories worldwide offer a highly technologically-advanced, personalized genetic testing from the field of nutrigenomics, a branch of science studying the effect of our nutrients on gene expression, which may influence both health and disease. Sadly, the test itself, despite being expensive, is all but useless to most patients as long as it is not accompanied by an interpretation and dietary recommendations. The Arcana Institute of Integrative Medicine led by dr. Magdalena Cubała-Kucharska possesses the knowledge and preparation enabling us to offer a new service: interpretation of an individual genetic profile performed in any laboratory, and choosing the correct supplementation and diet. Starting from March 1st, patients will be able to register with test results in order to […]

Intestinal problems in autism?

This notion has not yet reached mainstream penetration in the health service, yet, according to some sources, intestinal problems may affect up to 70 percent of autistic children! Why is the detection rate so low? Autistic children often have problems communicating, so their guardians do not see the problems which the children cannot articulate. The symptoms such as green stools, diarrhea, or constipation are often ignored by doctors. Problems with getting help also stem from a lack of special questionnaires for nonverbal people. The researchers from Johns Hopkins University have followed hundreds of studies concerning autistic children (and not focused on diet or the GI tract), of which they chose 84. They have judged them based on GI symptoms. The […]

Autism and Inflammation

We are still not sure what causes autism, although it seems to be a non-homogeneous and multi-factor disease. However, all of the disorders caused by autism are coupled with an inflammation in the central nervous system. In a study at Johns Hopkins University, researchers compared the brains of deceased autistic people to neurotypical brains. Based on the large sample size, it has been conclusively proven that there exists an abnormal and excessive immunological reaction in the central nervous system of autistic people—the same reaction as can be seen in the case of an inflammation. The anomalies are visible in the cells of the so-called microglia. The microglia consists of immune system cells, which are always present in the brain and […]